New Vaccine against Tuberclosis

A new vaccine against the deadly air-borne disease, tuberculosis, could be available in the next eight years. At present, the only available vaccine for the prevention of TB is Bacille-Calmette-Guérin (BCG), which was discovered almost 100 years ago.The World Health Organization (WHO) said that the world is finally waking up to the need for an effective new-age TB vaccine with 11 vaccine candidates for TB prevention in Phase I or Phase II trials and one immunotherapeutic vaccine in a Phase III trial. WHO said, “It is hoped that one or two of the candidates in a Phase II trial will enter a Phase III trial in the next three years, with the possibility of licensing at least one new vaccine by 2020.

A new vaccine that prevents TB could significantly reduce the enormous financial burden of treating drug-resistant TB – which can cost Rs 1 lakh per patient in India. India is home to about 73,000 drug-resistant TB patients. 

1.6% of resistant TB patients enrolled In a shocking disclosure, WHO has said that while India is home to 73,000 patients with multi-drug resistant TB, the health ministry notified just 2% of these cases as being resistant to drugs. Barely 1.6% of these MDR TB patients were enrolled for treatment.TB one of top killers of women After almost 100 years, there are hopes of a new tuberculosis vaccine. This could prevent the toll that the disease takes on individuals who are subjected to 18-24 months of medication with side effects that can be as severe as hearing loss or psychosis. In 2011, there were an estimated 8.7 million new cases of TB (13% co-infected with HIV) and 1.4 million people died from the disease, including almost one million deaths among HIV-negative individuals and 4.3 lakh among people who were HIV-positive. TB is one of the top killers of women, with 3 lakh deaths among HIV-negative women and 2 lakh mortalities among HIV-positive women last year.

Anti cancer effect of Broccoli (Brassica oleracea)

                               

                                         Anti cancer effect of Broccoli (Brassica oleracea)

Broccoli  is a common day to day used vegetable rich in sulforaphane which shows anti-cancer property against. The prostate cancer and many other forms of cancer. Another notable compound found in Broccoli is Raphanin (Raphanus sativus). Raphanin is the main sulfur component found in radish seeds of Raphanus sativus and is also found in broccoli and red cabbage. Raphanin inhibits activity of viruses, some fungi and various bacteria including  Staphylococus, Streptococus, Pneumococcus and Escherichia coli (see table). The effect is stronger against Gram-positive than Gram-negative bacteria and against DNA than RNA viruses; it is suppressed by serum and by sulfur compounds such as hydrogen sulfide, mercaptoacetic acid, cystine and glutathione. The antibacterial, antifungal and antiviral effects from consuming radishes were recognized in Traditional Chinese medicine.Given that Raphanin can be chiefly responsible for keeping the production of thyroxin and calcitonin in normal balance. Sulforaphane is an organosulfur compound that exhibits anti-cancer, and antimicrobial properties in experimental models. It is obtained from cruciferous vegetables such as broccoli, Brussels sprouts or cabbages. The enzyme myrosinase transforms glucoraphanin, a glucosinolate, into sulforaphane upon damage to the plant (such as from chewing). Young sprouts of broccoli and cauliflower are particularly rich in glucoraphanin. However raphanin can not be used as a positive therapeutic agent due to its toxic effect.

Effective on-

Prostate cancer, Viruses, Bacteria and fungal microorganisms. The vaccine for prostate cancer developed from Sulforaphane is in numerous clinical trials including a phase II trial and research on other disease’s are going on.

 

 

Some facts about pancreatic cancer

November is National Pancreatic Cancer Awareness Month. I hope each of you take the time to learn about this devastating cancer, in hopes to raise awareness. People aren’t as knowledgeable about pancreatic cancer as breast or prostate cancer, but it is just as a debilitating disease.31,800 Americans will die of pancreatic cancer this year32,180 Americans will be diagnosed with pancreatic cancer this year

• 32,180 Americans will be diagnosed with pancreatic cancer this year
• 31,800 Americans will die of pancreatic cancer this year
• Pancreatic cancer is the 4th ranked cause of cancer death
• only 23% of people diagnosed with be alive 1 year from diagnosis

• 4% of people diagnosed with pancreatic cancer will live reach the 5 year survival rate.

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